Flights from Santo Domingo to Guayaquil

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Cheap Santo Domingo - Guayaquil flight offers

Find cheap flight tickets and last-minute flight deals from Santo Domingo to Guayaquil

JetBlue Airways
Tue, 11/24 (SDQ) Santo Domingo -> (GYE) Guayaquil
JetBlue Airways
Sat, 11/28 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found 12 days ago
from $317
JetBlue Airways
Tue, 11/24 (SDQ) Santo Domingo -> (GYE) Guayaquil
JetBlue Airways
Mon, 11/30 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found Yesterday
from $338
Avianca
Fri, 02/19 (SDQ) Santo Domingo -> (GYE) Guayaquil
Avianca
Sun, 02/21 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found 9 days ago
from $385
Avianca
Mon, 11/30 (SDQ) Santo Domingo -> (GYE) Guayaquil
Avianca
Mon, 12/07 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found 9 days ago
from $443
Copa Airlines
Thu, 01/21 (SDQ) Santo Domingo -> (GYE) Guayaquil
Copa Airlines
Sat, 01/30 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found 9 days ago
from $445
Copa Airlines
Tue, 12/15 (SDQ) Santo Domingo -> (GYE) Guayaquil
Copa Airlines
Sun, 12/20 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found Yesterday
from $445
Copa Airlines
Fri, 11/13 (SDQ) Santo Domingo -> (GYE) Guayaquil
Copa Airlines
Wed, 11/18 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found Yesterday
from $446
Copa Airlines
Fri, 11/13 (SDQ) Santo Domingo -> (GYE) Guayaquil
Copa Airlines
Sun, 11/15 (GYE) Guayaquil -> (SDQ) Santo Domingo

Price found 3 days ago
from $452
Copa Airlines
Thu, 11/26 (SDQ) Santo Domingo -> (GYE) Guayaquil

Price found 9 days ago
from $230
Copa Airlines
Wed, 11/25 (SDQ) Santo Domingo -> (GYE) Guayaquil

Price found 2 days ago
from $230
Avianca
Wed, 12/23 (SDQ) Santo Domingo -> (GYE) Guayaquil

Price found 4 days ago
from $403

Info about flights from Santo Domingo to Guayaquil

Some useful info about flights from Santo Domingo to Guayaquil to help you plan your next trip

Best price last 15 days $230
Average flight duration 4h 30m
Cheapest month May
Average number of flights per week 1
First flight time 00:01
Last flight time 23:59

When is it best to fly from Santo Domingo to Guayaquil

Find out what is the best time of year to fly from Santo Domingo to Guayaquil

Nov $475
Dec $555
Jan $477
Feb $540
Mar $648
Apr $569
May $424
Jun $4,921
Jul $759
Aug $472
Sep $574
Oct $543
Most expensive month June
Average price $4,921
Cheapest month May
Average price $424
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

Top airlines on the route Santo Domingo - Guayaquil

Airlines providing flights to Guayaquil from Santo Domingo

How much is a flight from Santo Domingo to Guayaquil?

Depending on when you travel and how far in advance you book, fares between Santo Domingo and Guayaquil can differ a lot.

$230 is the best price recorded in the last 15 days.

Low-cost airlines offer competitive fares, but often add charges for extra services. Keep that in mind when planning your trip. Also, midweek departures may offer better deals than weekends.

Which airports near Santo Domingo or Guayaquil offer flights?

In many cases, using a nearby airport can improve your chances of finding direct flights or better rates.

  • Airports in Santo Domingo: Besides Santo Domingo - Las Américas, you can also try La Isabela.
  • Airports in Guayaquil: Guayaquil is the only airport in use at the moment.

Secondary airports can offer faster travel thanks to shorter lines and quicker boarding times than major ones.

Flights from Santo Domingo - Las Américas to Guayaquil

Plan your perfect flight from Santo Domingo to Guayaquil

Jetcost gives you full control over your flight search. Filter by date, time, duration, price, and airline. See round-trip and one-way options from low-cost and full-service carriers like Delta, United, American, and more.

Other popular destinations

Planning a trip to Ecuador? Other frequent searches include: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

Some airlines include baggage in the fare, others don’t — always check the details before booking. If you're looking for round-trip flights, you can easily see the most convenient combinations.

Frequently Asked Questions

Frequently asked questions about flights from Santo Domingo to Guayaquil.

How much does an airline ticket from Santo Domingo to Guayaquil cost?

The lowest price recorded in the last 15 days for a flight from Santo Domingo to Guayaquil is $230.

How far is Santo Domingo from Guayaquil?

Santo Domingo is about 1583 mi from Guayaquil.

What are the airports in Guayaquil?

Guayaquil has one airport: Guayaquil.

What are the airports in Santo Domingo?

Santo Domingo has another airport: La Isabela.

What are the most popular cities in Ecuador?

The most popular cities in Ecuador according to our users' searches are: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

When should I book a flight from Santo Domingo to Guayaquil?

The best time to book a flight from Santo Domingo to Guayaquil is 1 month in advance, while the worst time is 1 week in advance.

What is the cheapest month to fly from Santo Domingo to Guayaquil?

The cheapest month to fly from Santo Domingo to Guayaquil is May.

What is the most expensive month to fly from Santo Domingo to Guayaquil?

The most expensive month to fly from Santo Domingo to Guayaquil is June.

What is the best day of the week to fly from Santo Domingo to Guayaquil?

For flights from Santo Domingo to Guayaquil Wednesday is on average the cheapest day to fly, while Tuesday is the most expensive day to fly.