Cheap flights from Panama City to Guayaquil from $147

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Cheap Panama City - Guayaquil flight offers

Find cheap flight tickets and last-minute flight deals from Panama City to Guayaquil

Avianca
Sun, 07/05 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Thu, 07/16 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 7 days ago
from $336
Avianca
Mon, 07/06 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Fri, 07/17 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 9 days ago
from $338
Avianca
Tue, 07/14 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Tue, 07/21 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 4 days ago
from $339
Avianca
Wed, 06/24 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Tue, 06/30 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $339
Avianca
Sat, 07/04 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Wed, 07/15 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 9 days ago
from $344
Avianca
Wed, 07/01 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Thu, 07/09 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $345
Copa Airlines
Sun, 07/05 (PTY) Panama City -> (GYE) Guayaquil
Direct
Copa Airlines
Fri, 07/17 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 5 days ago
from $352
Avianca
Thu, 06/18 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Mon, 06/22 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $368
Avianca
Wed, 06/24 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 2 days ago
from $147
Avianca
Thu, 06/25 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 2 days ago
from $147
Avianca
Fri, 06/26 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 2 days ago
from $147
Avianca
Sat, 06/27 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 2 days ago
from $147
Avianca
Tue, 06/23 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 3 days ago
from $198
Avianca
Mon, 06/22 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 14 days ago
from $216
Avianca
Sun, 09/06 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 9 days ago
from $222
Avianca
Mon, 08/10 (PTY) Panama City -> (GYE) Guayaquil
Direct

Price found 13 days ago
from $224
Avianca
Sun, 07/05 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Thu, 07/16 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 7 days ago
from $336
Avianca
Mon, 07/06 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Fri, 07/17 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 9 days ago
from $338
Avianca
Tue, 07/14 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Tue, 07/21 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 4 days ago
from $339
Avianca
Wed, 06/24 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Tue, 06/30 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $339
Avianca
Sat, 07/04 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Wed, 07/15 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 9 days ago
from $344
Avianca
Wed, 07/01 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Thu, 07/09 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $345
Copa Airlines
Sun, 07/05 (PTY) Panama City -> (GYE) Guayaquil
Direct
Copa Airlines
Fri, 07/17 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 5 days ago
from $352
Avianca
Thu, 06/18 (PTY) Panama City -> (GYE) Guayaquil
Direct
Avianca
Mon, 06/22 (GYE) Guayaquil -> (PTY) Panama City
Direct

Price found 2 days ago
from $368

Info about flights from Panama City to Guayaquil

Some useful info about flights from Panama City to Guayaquil to help you plan your next trip

Best price last 15 days $147
Average flight duration 2h 16m
Cheapest month November
Average number of flights per week 20
First flight time 02:55
Last flight time 22:40

When is it best to fly from Panama City to Guayaquil

Find out what is the best time of year to fly from Panama City to Guayaquil

Jun $355
Jul $345
Aug $403
Sep $306
Oct $387
Nov $284
Dec $425
Jan $398
Feb $290
Mar $304
Apr $331
May $403
Most expensive month December
Average price $425
Cheapest month November
Average price $284
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

Top airlines on the route Panama City - Guayaquil

Airlines providing flights to Guayaquil from Panama City

How much is a flight from Panama City to Guayaquil?

Depending on when you travel and how far in advance you book, fares between Panama City and Guayaquil can differ a lot.

$147 is the best price recorded in the last 15 days.

Low-cost airlines offer competitive fares, but often add charges for extra services. Keep that in mind when planning your trip. Also, midweek departures may offer better deals than weekends.

Which airports serve Panama City and Guayaquil?

When planning a trip of about 777 mi, it's a good idea to check flights from surrounding airports too.

  • Airports in Panama City: Panama City is connected to 2 airports - Pacífico International Airport, Paitilla.
  • Airports in Guayaquil: The only active airport in Guayaquil is Guayaquil.

The closest airport isn’t always the cheapest — it’s worth checking the alternatives too. In some cities, smaller airports offer lower fares than the main ones.

Flights from Panama City - Tocumen to Guayaquil

Plan your perfect flight from Panama City to Guayaquil

Jetcost gives you full control over your flight search. Filter by date, time, duration, price, and airline. See round-trip and one-way options from low-cost and full-service carriers like Delta, United, American, and more.

Other popular destinations

Planning a trip to Ecuador? Other frequent searches include: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

Some airlines include baggage in the fare, others don’t — always check the details before booking. If you're looking for round-trip flights, you can easily see the most convenient combinations.

Frequently Asked Questions

Frequently asked questions about flights from Panama City to Guayaquil.

How much does an airline ticket from Panama City to Guayaquil cost?

The lowest price recorded in the last 15 days for a flight from Panama City to Guayaquil is $147.

How far is Panama City from Guayaquil?

Panama City is about 777 mi from Guayaquil.

What are the airports in Guayaquil?

Guayaquil has one airport: Guayaquil.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the most popular cities in Ecuador?

The most popular cities in Ecuador according to our users' searches are: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

When should I book a flight from Panama City to Guayaquil?

The best time to book a flight from Panama City to Guayaquil is 1 month in advance, while the worst time is 44 weeks in advance.

What is the cheapest month to fly from Panama City to Guayaquil?

The cheapest month to fly from Panama City to Guayaquil is November.

What is the most expensive month to fly from Panama City to Guayaquil?

The most expensive month to fly from Panama City to Guayaquil is December.

What is the best day of the week to fly from Panama City to Guayaquil?

For flights from Panama City to Guayaquil Sunday is on average the cheapest day to fly, while Friday is the most expensive day to fly.