Planning a flight from Santiago de Chile to Guayaquil?

Flight prices from Santiago de Chile to Guayaquil change depending on demand and time of booking.

The lowest fare seen in the past 15 days was $149.

Many users find better fares by booking several weeks in advance. In fact, for many routes, booking early is one of the best ways to save.

Are there multiple airports in Santiago de Chile and Guayaquil?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Santiago de Chile: Only Santiago de Chile operates in this city.
• Airports in Guayaquil: Guayaquil is the only airport currently running.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Explore flights from Santiago de Chile to Guayaquil your way

On Jetcost, you can filter by round-trip or one-way, time of day, airline, number of stops, and even by agency like eDreams or Expedia. Options include Delta, United, American, and more.

Other popular destinations

Also interested in Ecuador? Check out: Cuenca, Galapagos Islands, Guayaquil, Manta (Eloy Alfaro), Quito.

If you’re flexible with dates, try checking the days before and after to see if prices vary. Some routes are offered by multiple agencies — comparing fares can really pay off.