Flights from Santo Domingo to Panama City

Flights tailored to your budget

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Cheap Santo Domingo - Panama City flight offers

Find cheap flight tickets and last-minute flight deals from Santo Domingo to Panama City

Avianca
Mon, 02/22 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sun, 02/28 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 2 days ago
from $263
Avianca
Mon, 02/01 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Wed, 02/03 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 3 days ago
from $263
Avianca
Wed, 02/24 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sun, 02/28 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found Yesterday
from $263
Avianca
Mon, 03/22 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Wed, 03/31 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 4 days ago
from $300
Avianca
Tue, 11/10 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sat, 11/14 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 10 days ago
from $308
Copa Airlines
Fri, 12/18 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Copa Airlines
Thu, 12/31 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 6 days ago
from $317
Avianca
Tue, 11/10 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sat, 11/21 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 9 days ago
from $322
Avianca
Fri, 06/18 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Mon, 06/21 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 8 days ago
from $331
American Airlines
Thu, 11/12 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found Yesterday
from $92
Avianca
Fri, 11/27 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found 13 days ago
from $234
Wingo
Tue, 03/02 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found 2 days ago
from $293
Arajet
Tue, 03/16 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found 2 days ago
from $297
Arajet
Tue, 04/20 (SDQ) Santo Domingo -> (PTY) Panama City

Price found 2 days ago
from $297
Arajet
Tue, 02/16 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found 5 days ago
from $298
Arajet
Tue, 02/02 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found Yesterday
from $303
American Airlines
Wed, 06/30 (SDQ) Santo Domingo -> (PTY) Panama City
Direct

Price found 11 days ago
from $304
Avianca
Wed, 02/24 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sun, 02/28 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found Yesterday
from $263
Avianca
Mon, 02/01 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Wed, 02/03 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 3 days ago
from $263
Avianca
Mon, 02/22 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sun, 02/28 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 2 days ago
from $263
Avianca
Mon, 03/22 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Wed, 03/31 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 4 days ago
from $300
Avianca
Tue, 11/10 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sat, 11/14 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 10 days ago
from $308
Copa Airlines
Fri, 12/18 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Copa Airlines
Thu, 12/31 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 6 days ago
from $317
Avianca
Tue, 11/10 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Sat, 11/21 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 9 days ago
from $322
Avianca
Fri, 07/16 (SDQ) Santo Domingo -> (PTY) Panama City
Direct
Avianca
Tue, 07/20 (PTY) Panama City -> (SDQ) Santo Domingo
Direct

Price found 8 days ago
from $331

Info about flights from Santo Domingo to Panama City

Some useful info about flights from Santo Domingo to Panama City to help you plan your next trip

Best price last 15 days $78
Average flight duration 3h 15m
Cheapest month October
Average number of flights per week 91
First flight time 00:30
Last flight time 23:51

When is it best to fly from Santo Domingo to Panama City

Find out what is the best time of year to fly from Santo Domingo to Panama City

Nov $595
Dec $537
Jan $700
Feb $610
Mar $1,025
Apr $952
May $1,100
Jun $592
Jul $588
Aug $699
Sep $580
Oct $458
Most expensive month May
Average price $1,100
Cheapest month October
Average price $458
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

Top airlines on the route Santo Domingo - Panama City

Airlines providing flights to Panama City from Santo Domingo

Find out what a flight from Santo Domingo to Panama City might cost

Prices vary based on date, airline, and availability. Compare several options if you're flying between Santo Domingo and Panama City.

$78 is the best price recorded in the last 15 days.

Try shifting your departure forward or backward by a day to find better options. If you’re looking for a good deal, consider flying outside peak hours as well.

Flights between Santo Domingo and Panama City: which airports can you choose?

The distance between Santo Domingo and Panama City is about 917 mi. Checking alternative airports can help lower the total cost of your trip.

  • Airports in Santo Domingo: Santo Domingo has one more option besides Santo Domingo - Las Américas - La Isabela.
  • Airports in Panama City: Panama City is served by 2 airports - Pacífico International Airport, Paitilla.

Choosing airports with fast connections to the city center can cut down total travel time. You can compare all flights from Santo Domingo airports to find the best option.

Flights from Santo Domingo - Las Américas to Panama City - Tocumen

Customize your flight from Santo Domingo to Panama City

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from Delta, American, United, Expedia, eDreams, and more.

Other popular destinations

Thinking about Panama? You might also consider: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.

Frequently Asked Questions

Frequently asked questions about flights from Santo Domingo to Panama City.

How much does an airline ticket from Santo Domingo to Panama City cost?

The lowest price recorded in the last 15 days for a flight from Santo Domingo to Panama City is $78.

How far is Santo Domingo from Panama City?

Santo Domingo is about 917 mi from Panama City.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the airports in Santo Domingo?

Santo Domingo has another airport: La Isabela.

What are the most popular cities in Panama?

The most popular cities in Panama according to our users' searches are: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

When should I book a flight from Santo Domingo to Panama City?

The best time to book a flight from Santo Domingo to Panama City is 1 month in advance, while the worst time is 8 weeks in advance.

What is the cheapest month to fly from Santo Domingo to Panama City?

The cheapest month to fly from Santo Domingo to Panama City is October.

What is the most expensive month to fly from Santo Domingo to Panama City?

The most expensive month to fly from Santo Domingo to Panama City is May.

What is the best day of the week to fly from Santo Domingo to Panama City?

For flights from Santo Domingo to Panama City Saturday is on average the cheapest day to fly, while Thursday is the most expensive day to fly.