Cheap flights from Panama City to Chicago O'Hare from $413

Flights tailored to your budget

Selected dates may not give results due to COVID-19. We suggest you change the dates.
Multi-city Round trip One way
Round trip
One way
Multi-city
From
No results match your search criteria
To
No results match your search criteria
{{ weekDay }}
Dates
{{ panel.label }}
Looking for a one-way flight?

Flexible dates can save you money

Explore nearby dates to find lower fares

{{ fromDate | dateToLongNamedDate }}
?
Flexible dates
Depart {{ flexibleFromDateLabel }}
{{ option.label }}
?
Return {{ flexibleToDateLabel }}
{{ option.label }}
Passengers / Class
Number of passengers
Adults
{{ adults }}
Children
{{ children }}
Infants
{{ infants }}
Class
Economy
Available for Economy only
New Multi-city experience

Discover a new Multi-city search experience from Jetcost, designed to handle more complex itineraries. By continuing, you’ll be taken to a dedicated page powered by Kiwi.com.

Cheap Panama City - Chicago O'Hare flight offers

Find cheap flight tickets and last-minute flight deals from Panama City to Chicago O'Hare

American Airlines
Thu, 08/20 (PTY) Panama City -> (ORD) Chicago
Direct
American Airlines
Mon, 08/31 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 2 days ago
from $413
Avianca
Thu, 09/10 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Thu, 09/17 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 8 days ago
from $479
Avianca
Tue, 11/03 (PTY) Panama City -> (ORD) Chicago
Avianca
Tue, 11/17 (ORD) Chicago -> (PTY) Panama City
Price found Yesterday
from $606
Avianca
Thu, 06/10 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Fri, 06/18 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 8 days ago
from $648
Avianca
Sat, 09/26 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Wed, 09/30 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 15 days ago
from $725
Avianca
Fri, 01/22 (PTY) Panama City -> (ORD) Chicago
Avianca
Tue, 01/26 (ORD) Chicago -> (PTY) Panama City
Price found 15 days ago
from $739
Avianca
Fri, 10/30 (PTY) Panama City -> (ORD) Chicago
Avianca
Sun, 11/15 (ORD) Chicago -> (PTY) Panama City
Price found 9 days ago
from $739
Avianca
Wed, 09/09 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Wed, 09/23 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 5 days ago
from $739
United
Mon, 11/23 (PTY) Panama City -> (ORD) Chicago
Direct
Price found 3 days ago
from $1,107
American Airlines
Thu, 08/20 (PTY) Panama City -> (ORD) Chicago
Direct
American Airlines
Mon, 08/31 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 2 days ago
from $413
Avianca
Thu, 09/10 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Thu, 09/17 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 8 days ago
from $479
Avianca
Thu, 06/10 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Fri, 06/18 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 8 days ago
from $648
Avianca
Sat, 09/26 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Wed, 09/30 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 15 days ago
from $725
Avianca
Wed, 09/09 (PTY) Panama City -> (ORD) Chicago
Direct
Avianca
Wed, 09/23 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 5 days ago
from $739
United
Tue, 09/08 (PTY) Panama City -> (ORD) Chicago
Direct
United
Tue, 09/22 (ORD) Chicago -> (PTY) Panama City
Direct
Price found 5 days ago
from $785

Info about flights from Panama City to Chicago O'Hare

Some useful info about flights from Panama City to Chicago O'Hare to help you plan your next trip

Best price last 15 days $413
Average flight duration 5h 46m
Cheapest month April
Average number of flights per week 4
First flight time 02:26
Last flight time 22:29

When is it best to fly from Panama City to Chicago O'Hare

Find out what is the best time of year to fly from Panama City to Chicago O'Hare

Aug $495
Sep $574
Oct $739
Nov $756
Dec $412
Jan $739
Feb $513
Mar $425
Apr $365
May $575
Jun $647
Jul $547
Most expensive month November
Average price $756
Cheapest month April
Average price $365
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

Top airlines on the route Panama City - Chicago O'Hare

Airlines providing flights to Chicago O'Hare from Panama City

American Airlines
American Airlines
Avianca
Avianca
Copa Airlines
Copa Airlines
DELTA
DELTA
United
United

How to get the best price from Panama City to Chicago O'Hare?

Depending on when you travel and how far in advance you book, fares between Panama City and Chicago can differ a lot.

$413 is the lowest fare found in the past 15 days.

Search engines like Jetcost can highlight price changes in just seconds. For example, some users find better prices by flying on one day of the week over another — try several searches to spot the cheapest day.

Which airports serve Panama City and Chicago?

When planning a trip of about 2331 mi, it's a good idea to check flights from surrounding airports too.

  • Airports in Panama City: Panama City is connected to 2 airports - Pacífico International Airport, Paitilla.
  • Airports in Chicago: Chicago offers flights from 3 airports - Midway, O'Hare, Rockford.

The closest airport isn’t always the cheapest — it’s worth checking the alternatives too. In some cities, smaller airports offer lower fares than the main ones.

Flights from Panama City - Tocumen to Chicago - O'Hare

Plan your journey from Panama City to Chicago O'Hare with ease

Use Jetcost to tailor your search — direct or connecting flights, round-trip or one-way, filtered by airline, price, travel time, or agency.

Other popular destinations

Exploring options in United States? These cities are trending: Houston, Los Angeles, Miami, New York City, Orlando.

Flight availability can change quickly — refresh the results if you’ve been away from the page for a while.
Frequently Asked Questions

Frequently asked questions about flights from Panama City to Chicago O'Hare.

How much does an airline ticket from Panama City to Chicago O'Hare cost?

The lowest price recorded in the last 15 days for a flight from Panama City to Chicago O'Hare is $413.

How far is Panama City from Chicago?

Panama City is about 2331 mi from Chicago.

What are the airports in Chicago?

Chicago has 3 airports: Midway, O'Hare, Rockford.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the most popular cities in United States?

The most popular cities in United States according to our users' searches are: Houston, Los Angeles, Miami, New York City, Orlando.

When should I book a flight from Panama City to Chicago?

The best time to book a flight from Panama City to Chicago is 1 month in advance, while the worst time is 19 weeks in advance.

What is the cheapest month to fly from Panama City to Chicago?

The cheapest month to fly from Panama City to Chicago is April.

What is the most expensive month to fly from Panama City to Chicago?

The most expensive month to fly from Panama City to Chicago is November.

What is the best day of the week to fly from Panama City to Chicago?

For flights from Panama City to Chicago Monday is on average the cheapest day to fly, while Saturday is the most expensive day to fly.