Cheap flights from Houston to Panama City from $355

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Cheap Houston - Panama City flight offers

Find cheap flight tickets and last-minute flight deals from Houston to Panama City

United
Wed, 09/09 (HOU) Houston -> (PTY) Panama City
Direct
United
Mon, 09/21 (PTY) Panama City -> (HOU) Houston
Direct

Price found 10 days ago
from $269
United
Fri, 08/07 (HOU) Houston -> (PTY) Panama City
Direct
United
Fri, 08/14 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $302
Avianca
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Tue, 06/30 (PTY) Panama City -> (HOU) Houston
Direct

Price found 5 days ago
from $355
Avianca
Mon, 06/29 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Fri, 07/10 (PTY) Panama City -> (HOU) Houston
Direct

Price found 5 days ago
from $431
DELTA
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
DELTA
Thu, 06/25 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $436
Avianca
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Wed, 06/24 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $441
United
Wed, 09/09 (HOU) Houston -> (PTY) Panama City
Direct
United
Mon, 09/21 (PTY) Panama City -> (HOU) Houston
Direct

Price found 10 days ago
from $269
United
Fri, 08/07 (HOU) Houston -> (PTY) Panama City
Direct
United
Fri, 08/14 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $302
Avianca
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Tue, 06/30 (PTY) Panama City -> (HOU) Houston
Direct

Price found 5 days ago
from $355
Avianca
Mon, 06/29 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Fri, 07/10 (PTY) Panama City -> (HOU) Houston
Direct

Price found 5 days ago
from $431
DELTA
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
DELTA
Thu, 06/25 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $436
Avianca
Mon, 06/22 (HOU) Houston -> (PTY) Panama City
Direct
Avianca
Wed, 06/24 (PTY) Panama City -> (HOU) Houston
Direct

Price found 2 days ago
from $441

Info about flights from Houston to Panama City

Some useful info about flights from Houston to Panama City to help you plan your next trip

Best price last 15 days $355
Average flight duration 4h 13m
Cheapest month September
Average number of flights per week 3
First flight time 06:03
Last flight time 20:23
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Top airlines on the route Houston - Panama City

Airlines providing flights to Panama City from Houston

Looking for the price of a flight from Houston to Panama City?

There’s no fixed price — fares between Houston and Panama City can vary a lot by day or time.

$355 is the best price recorded in the last 15 days.

It’s often useful to check whether nearby airports offer better fares. Flying during less crowded periods also increases your chances of finding good deals.

Are there alternative airports near Houston and Panama City?

The two cities are about 1754 mi apart. Looking beyond the main airport might reveal better options.

  • Airports in Houston: Alongside Houston - William P. Hobby, there's also George Bush Intercontinental.
  • Airports in Panama City: Panama City is served by 2 airports - Pacífico International Airport, Paitilla.

Many smaller airports are connected by direct buses or shuttles, often at low cost. If Panama City has more than one airport, you can pick the most convenient for your destination.

Flights from Houston - William P. Hobby to Panama City - Tocumen

Plan your journey from Houston to Panama City with ease

Use Jetcost to tailor your search — direct or connecting flights, round-trip or one-way, filtered by airline, price, travel time, or agency.

Other popular destinations

Exploring options in Panama? These cities are trending: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

Flight availability can change quickly — refresh the results if you’ve been away from the page for a while.

Frequently Asked Questions

Frequently asked questions about flights from Houston to Panama City.

How much does an airline ticket from Houston to Panama City cost?

The lowest price recorded in the last 15 days for a flight from Houston to Panama City is $355.

How far is Houston from Panama City?

Houston is about 1754 mi from Panama City.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the airports in Houston?

Houston has another airport: George Bush Intercontinental.

What are the most popular cities in Panama?

The most popular cities in Panama according to our users' searches are: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

When should I book a flight from Houston to Panama City?

The best time to book a flight from Houston to Panama City is 1 month in advance, while the worst time is 4 weeks in advance.

What is the cheapest month to fly from Houston to Panama City?

The cheapest month to fly from Houston to Panama City is September.

What is the most expensive month to fly from Houston to Panama City?

The most expensive month to fly from Houston to Panama City is February.

What is the best day of the week to fly from Houston to Panama City?

For flights from Houston to Panama City Wednesday is on average the cheapest day to fly, while Monday is the most expensive day to fly.