What’s the cost of a flight from Saint Louis to Greenville?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Saint Louis and Greenville/Spartanburg.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

What are the airport options between Saint Louis and Greenville/Spartanburg?

If both departure and destination cities offer multiple airports, comparing them can help you save time and money.

• Airports in Saint Louis: Saint Louis - Lambert is currently the only airport available.
• Airports in Greenville/Spartanburg: Greenville/Spartanburg has one airport operating, Greenville/Spartanburg.

Some airports have different terminals for low-cost and traditional airlines — knowing in advance can save time. You can filter results to see only the airports that suit you.

Customize your flight from Saint Louis to Greenville

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from Delta, American, United, Expedia, eDreams, and more.

Other popular destinations

Thinking about United States? You might also consider: Atlanta, Los Angeles, Miami, New York City, Orlando.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.