How much is a flight from Des Moines to San Francisco?

There’s no fixed price — fares between Des Moines and San Francisco can vary a lot by day or time.

$113 is the lowest fare found in the past 15 days.

Flying during the week can be more affordable, as weekend flights tend to be pricier. Also consider demand and availability: the last remaining seats often come at higher fares!

Is there more than one airport in Des Moines or San Francisco?

Even short-haul routes can benefit from considering secondary airports. It may open up more flight times or cheaper fares.

• Airports in Des Moines: Only Des Moines is currently operational.
• Airports in San Francisco: San Francisco is the only airport in operation.

Airports with more daily flights offer more flexibility if plans change or delays occur. If you’re flexible, consider airports near San Francisco as well.

Smart ways to search flights from Des Moines to San Francisco

Use Jetcost to view tailored results based on what you care about — time, duration, number of stops, or even your preferred booking agency. Results include carriers like American, Delta, United, and more.

Other popular destinations

Flying to United States? Other travelers also searched: Las Vegas, Los Angeles, Miami, New York City, Orlando.

Prefer non-stop flights? Just activate the filter to skip unnecessary layovers. If your dates are flexible, you can also explore different departure and return combinations to find the best fit.