How much should you expect to spend for a flight from Des Moines to Phoenix?

Flight prices from Des Moines to Phoenix change depending on demand and time of booking.

$76 is the lowest fare found in the past 15 days.

Studies show that flying midweek — like on a Tuesday or Wednesday — can be cheaper than weekend flights. Still, airfares change frequently, so check updated prices on Jetcost.

Are there multiple airports in Des Moines and Phoenix?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Des Moines: Only Des Moines operates in this city.
• Airports in Phoenix: Mesa Gateway is a secondary airport to Phoenix - Sky Harbor International.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Customize your flight from Des Moines to Phoenix

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from Delta, American, United, Expedia, eDreams, and more.

Other popular destinations

Thinking about United States? You might also consider: Las Vegas, Los Angeles, Miami, New York City, Orlando.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.