How much is a ticket from Des Moines to Guadalajara?

Depending on when you travel and how far in advance you book, fares between Des Moines and Guadalajara can differ a lot.

The lowest fare seen in the past 15 days was $146.

If you’re flexible with timing, consider overnight flights — they often cost less and are less crowded. Exploring multiple date and time combinations can help you find the cheapest solution.

Planning flights between Des Moines and Guadalajara? Don’t forget the airport options

Especially when flying to medium or large cities, it's worth checking all possible airport combinations before booking.

• Airports in Des Moines: Des Moines is the only airport in this city.
• Airports in Guadalajara: Only Guadalajara - Miguel Hidalgo y Costilla is currently available.

Check for differences in transport costs to and from each airport — they affect your total spend. Choosing the right airport can make a real difference in price and timing.

Match your flight search to your preferences: Des Moines – Guadalajara

Jetcost makes it easy to find the right flight. Set filters for flight time, price, number of stops, and preferred airline. You’ll see offers from Expedia, Delta, United, American, and more.

Other popular destinations

Thinking about traveling to Mexico? Other users also viewed: Cancun, Guadalajara, Mexico City, Monterrey, Puerto Vallarta.

Don’t forget to check change or cancellation policies, especially if your plans aren’t final. For a more targeted search, you can also set price limits directly in the filters.